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br Discussion The use of co
2020-07-28
Discussion The use of co-translational incorporation during fermentation [27] to introduce Hyp residues instead of Pro residues in a bacterial collagen has been demonstrated. Inclusion of NaCl in the medium further increases the level of Hyp incorporation. It has been proposed [27] that this is d
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If the level of elastase
2020-07-27
If the level of elastase is unknown, but the level of CBG and CBG* is know, one is able to use the approximation . The results from fitting k (or more generally n) individually to the data of four normal individuals in Section 3.3 show that the model is able to fit data very well. The good performan
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br AAA pathophysiology The arterial wall comprises three lay
2020-07-27
AAA pathophysiology The arterial wall comprises three layers: tunica intima, media and adventitia. Specific cell types characterize each layer: the innermost layer, tunica intima, mostly consists of endothelial cells (EC). The media layer is dominated by smooth muscle cells (SMC), elastin- and co
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Nicotine dependence drives the habit of smoking which
2020-07-27
Nicotine dependence drives the habit of smoking, which causes a heavy load of disease and death, as smoking is one of the largest contributors to preventable morbidity and mortality (GBD 2015 Risk Factors Collaborators, 2016; World Health Organization(WHO), 2017). Inhaled nicotine reaches the brain,
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In this work we focus
2020-07-27
In this work we focus on identifying the protein responsible for the COX-2 like activity in Leishmania mexicana, as previous studies have reported the presence of different prostaglandins in several Leishmania species [13,14,27]. We demonstrate the presence of a protein with an approximate molecular
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Using characteristic features of ECM proteins and a computat
2020-07-27
Using characteristic features of ECM proteins and a computational pipeline combining interrogation of protein and gene databases, we previously defined the matrisome as the ensemble of ECM and ECM-associated proteins [[16], [17], [18]]. In mammals, the matrisome represents 4% of the genome, or appro
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br Acknowledgements br Introduction Lung cancer treatment st
2020-07-25
Acknowledgements Introduction Lung cancer treatment strategies, especially molecular targeted therapy, have progressed rapidly. However, most established treatments are for adenocarcinoma of the lung, not for squamous cell carcinoma (SQCC). SQCC constitutes approximately 30% of lung cancers, w
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br These component origins have been chosen
2020-07-25
These component origins have been chosen as they binimetinib mg are well-defined options related to developing with components (see for example Morisio and Torchiano (2002); Carney and Long (2000) and Gacek and Arief (2004)). The individual component origins (COTS, OSS, in-house developed compon
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Furthermore software engineering practices are important for
2020-07-25
Furthermore, software engineering practices are important for addressing productivity problems in scientific software. Even though the speed of the hardware is rapidly increasing, the additional complexity makes it more difficult for scientists to be productive developers. According to Faulk et al.,
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In rodent models the loss of estrogens through ovariectomy h
2020-07-25
In rodent models, the loss of estrogens through ovariectomy has been shown to promote the development of intracranial aneurysms. Conversely, the administration of an 3mb sale receptor beta agonist restores its protective effect, but is abolished with the introduction of a nitric oxide synthase inhi
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In a study performed simultaneously by another group EWS FLI
2020-07-24
In a study performed simultaneously by another group, EWS-FLI-1 introduction into unsorted murine bone marrow-derived Fungicidin resulted in tumors with various phenotypes including one that is consistent with that of Ewing sarcoma [68]. The tumors expressed markers associated with Ewing sarcoma an
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Introduction Enzymes have higher selectivity specificity and
2020-07-24
Introduction Enzymes have higher selectivity, specificity and efficiency than chemical catalysts. Due to their properties and their green chemistry, biocatalysts are widely used in food, textile and pharmaceutical industry [1], [2]. A high efficient biocatalyst for industrial applications must be s
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br Acknowledgments br Multicellular organisms respond rapidl
2020-07-24
Acknowledgments Multicellular organisms respond rapidly, and adapt to cellular stress to maximize cell survival. The cellular stress response, also called (ISR), is universally conserved and independent of the stressor. ISR induces rapid, transient reprogramming of cellular protein translation
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Methods br Results br Discussion In
2020-07-24
Methods Results Discussion In this study we make the novel observation that villin-1 and gelsolin are down-regulated in response to diverse cellular stressors, including bacteria associated with the pathogenesis of CD. The high plasticity and dynamics of the Fluorescein TSA Fluorescence Syste
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In the present study synthesis of Bi MoO nanoplates
2020-07-24
In the present study, synthesis of Bi2MoO6 nanoplates via DNA-templated hydrothermal method has been undertaken. The synthesis was done through the hydrothermal method by means of the reaction of bismuth nitrate pentahydrate (Bi(NO3)3·5H2O) with sodium molybdate dihydrate (Na2MoO4·2H2O) precursor in
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