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Both meiotic COs and NCOs require DNA synthesis current
2020-05-16
Both meiotic COs and NCOs require DNA synthesis, current data from sequencing also suggest that COs require more DNA synthesis than NCO 63., 64., 65.. However, analysis of the role of DNA synthesis in NCOs remains relatively uncharacterized. Emerging evidence points to a role for either Polδ or Polε
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In this study new and
2020-05-16
In this study, new and more extended tables of parameters were estimated for pure fluids and binary mixtures that are relevant to biodiesel systems. Also, calculations for glyceride systems will be shown, which is a topic not investigated before with the CPA model. As before [21], [22], [23], [24],
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br Conclusion This patient was
2020-05-15
Conclusion This patient was hypercoaguable as evidenced by a lower extremity DVT, pulmonary emboli, and a splenic infarct. Excluding acute CMV infectious mononucleosis, she had no disorders predisposing to splenic infarcts.4, 5 In this case, CMV infectious mononucleosis was accompanied by CMV lun
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To predict levels of SCF assembly Liu et al first
2020-05-15
To predict levels of SCF assembly, Liu et al. (2018) first quantified the remaining necessary kinetic parameters and derived a model in combination with known functions and concentrations of components. The model agrees astonishingly well with many experimental observables. In terms of SCF assembly,
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igf ir Introduction The number of patients with type diabete
2020-05-15
Introduction The number of patients with type 2 diabetes is increasing globally, and has become a serious public health problem. Type 2 diabetic patients exhibit a higher risk of bone fracture [1]. In addition, clinical studies have indicated that increased fracture risk is associated with long-ter
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Consistent with the known tolerance of the Suzuki Miyaura re
2020-05-15
Consistent with the known tolerance of the Suzuki–Miyaura reaction to a wide range of aryl substituents, we subsequently found that the commercially available 3-hydroxyphenylboronic ARM1 pinacol ester () could be coupled to , to give directly and in comparable yield. Smooth conversion of into wa
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Compound was synthesized by the directed
2020-05-15
Compound () was synthesized by the directed -metallation procedure (DOM) at the stage of the amide using butyl lithium and dry ice as CO source for the introduction of the carboxylic group. Thiophene amides were prepared from commercial 3-thiophenecarboxylic Pirfenidone by conversion into the acid c
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Methylated CpGs can recruit transcriptional co repressors to
2020-05-15
Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing DGAT-1 inhibitor mg structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared to Mr (Fig. 3
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The use of AACSB accreditation as an
2020-05-15
The use of AACSB accreditation as an indicator of expected performance on the CPA exam has been examined by prior studies (e.g. Barilla et al., 2008, Boone et al., 2006, Grant et al., 2002, Howell and Heshizer, 2006, Lindsay and Campbell, 2003, Marts et al., 1998). While these studies are based on d
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It should also be noted that remarkable individual
2020-05-15
It should also be noted that remarkable individual differences in extinguished fear bradycardia (i.e., CS+E vs. CS−E) during initial Day 2 recall test were observed, particularly within Met carriers. Exploratory analyses revealed that these individual differences were partly driven by the level of r
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The sequence identity of CYP A with CYP A
2020-05-14
The sequence identity of CYP3A163 with CYP3A sequences from other species is maximum in reptiles ranging (75-91)%, gradually decreasing from Benzoylmesaconitine receptor (63-71)% to mammals 62% to downwards based on evolutionary distances. The high level of homology with CYP3A77 in Alligator missis
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br COTSget based Architectures This section describes
2020-05-14
COTSget-based Architectures This section describes how our COTSget-based architectures are defined. We use a design inspired by MDE to build a Domain-Specific Language (DSL) of the architecture, as can be seen in the metamodel of Fig. 3. This metamodel defines the abstract syntax of our DSL and i
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br Disclosure statement br Acknowledgment This work was supp
2020-05-14
Disclosure statement Acknowledgment This work was supported by the National Natural Science Foundation of China (81270704, 81330018). Background Over-expression of cyclooxygenase-2 (COX-2) is common in many malignancies including non-small cell lung cancer (NSCLC) and is associated with po
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It is particularly notable that CYP D appears to
2020-05-14
It is particularly notable that CYP2D6 appears to be the most stable of the major CYP450 1,3-PBIT dihydrobromide in its expression over time in vitro and appears to be least affected by culture conditions and sample to sample variability (i.e., CYP2D6 expression is remarkably consistent over time a
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br Conflicts of interest br Financial support NZ
2020-05-14
Conflicts of interest Financial support NZ is an Established Investigator of the Dutch Heart Foundation (2013T111) and is supported by an ERC Consolidator grant (617376) from the European Research Council and by a Vici grant from the Netherlands Organization for Scientific Research (NWO; 91818
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