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Henderson et al reported that allergen induced airway
2019-09-16
Henderson et al. [20] reported that allergen-induced airway remodeling was blocked by the CysLT1 receptor antagonist montelukast. The development of epithelial thickening and mucus accumulation at relatively small L-690,330 was also suppressed by montelukast. The CysLT2 receptor antagonist BayCysLT
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AC220 ic50 To date methods for the
2019-09-16
To date, methods for the simultaneous analysis of multiple probe drugs in the plasma have been described by using HPLC-DAD or LC–MS/MS. Although previous cocktail methods have used combinations of those four or other probe drugs with LC–MS/MS methods, most of those studies focused on only the analys
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The defining molecular feature of Ewing sarcoma is the
2019-09-12
The defining molecular feature of Ewing sarcoma is the characteristic EWSR1/ETS fusion protein, most commonly involving EWSR1 and FLI1 (Delattre et al., 1992, May et al., 1993).
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br Introduction The dopaminergic system
2019-09-11
Introduction The dopaminergic system and its projections including both the prefrontal NHS-Biotin (PFC) and striatum are known as being crucial to synaptic plasticity, skill acquisition and higher order functions (e.g., working memory and cognitive control; Matsumoto et al., 2003).
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br Methods Ventricular cardiomyocytes from adult male Wistar
2019-09-10
Methods Ventricular cardiomyocytes from adult male Wistar rats were isolated using a standard enzymatic digestion [11].
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Asteroids can provide an abundant supply of
2019-09-09
Asteroids can provide an abundant supply of other resources, such as carbon, nitrogen, or calcium compounds, but will only be useful once the space economy is sufficiently developed to provide economically interesting uses for them.
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The identification of CCR B
2019-09-07
The identification of CCR6+ GNF 5 within the LZ as direct progenitors of MBCs provides a new window into the evolution of immune responses. In practical terms
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On the other hand p responds to
2019-09-06
On the other hand, p38 responds to environmental stress, including ultraviolet light, heat, osmotic shock, and inflammatory cytokines (Pearson et al., 2001, Kumar et al., 2003), and is activated in astrocytes after ischemia-like injury (Yung and Tolkovsky, 2003, Niu et al., 2009).
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The mechanisms by which Cav enhances
2019-09-05
The mechanisms by which Cav-1 enhances embryonal tumor progression are currently unknown.
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Previous studies have demonstrated the role of the COMT Val
2019-09-04
Previous studies have demonstrated the role of the COMT Val158Met in response to positive and negative emotional stimuli (Bouhuys et al., 1999, Cohn et al., 2009), a fundamental process involved in well-being (Diener et al., 2009a, Diener et al., 1999, Gross and John, 2003).
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MK3102 br Material and methods br Results and discussion br
2019-09-03
Conclusions Prostanoid-E receptor selective antagonists that inhibit EP2 or EP4 receptor activities may be used as a pharmacological strategy to limit cyst formation and ADPKD progression.
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Traditionally serum triglycerides have been measured in the
2019-09-02
Traditionally, serum triglycerides have been measured in the clinic in the fasted state in order to reduce variability and also to facilitate the calculation of LDL-cholesterol via the Friedewald equation, which was derived using fasted samples (Warnick and Nakajima, 2008).
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br Discussion Our data demonstrate that the
2019-08-30
Discussion Our data demonstrate that the bicyclam AMD3100 strongly interacts with CXCR-4, whereas DS and AR177, two other compounds that also interfere with virus entry into the TLR3 (and interfere with virus binding), do not.
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SU11274 Herein we further established a dynamic DNA self
2019-08-29
Herein, we further established a dynamic DNA self-assembly activated hemin-mimetic enzymes system by embedding DNA-hemin into an entropy-driven DNA-assembly for fluorescent biosensing.
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Quercetin competitively inhibited BFC activity in human reco
2019-08-28
Quercetin competitively inhibited BFC activity in human recombinant cDNA-expressed CYP3A4 with Ki=15.4±1.52μM, and myricetin noncompetitively with Ki=74.6±7.99μM (Fig. 4).
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