Because of the important role of the

2019-08-19

Because of the important role of the DDB1-CUL4B interaction for CUL4B-based E3 ligases, disruption of the DDB1-CUL4B interaction could be an effective approach to treat cancer.

br Methods br Results br Discussion There are two

2019-08-17

Discussion There are two particularly important facets of the present ERK findings relevant to drug conditioning.

br EBI structure and expression The gene

2019-08-16

EBI2 structure and expression The gene encoding EBI2 was originally identified together with EBI1 (CCR7) as the most highly upregulated gene in Epstein–Barr virus-infected Burkitt\'s lymphoma cells [18].

(-)-JQ1 It has been shown that DAPK

2019-08-15

It has been shown that DAPK induces cell death through an increase in DAPK catalytic activity and subsequent phosphorylation of target proteins (Shang et al., 2005, Yamamoto et al., 2002), but its multidomain structure enables also a close physical interaction with other proteins (Bialik and Kimchi, 2006).

br Results br Discussion Here we establish

2019-08-14

Discussion Here we establish a key kinase cascade that acts at PCs to promote homolog pairing and synapsis.

Introduction Ubiquitylation is a post translational modifica

2019-08-13

Introduction Ubiquitylation is a post-translational modification which impacts almost every biological process in the cell.

Hello world!

2018-07-29