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Asteroids can provide an abundant supply of
2019-09-09
Asteroids can provide an abundant supply of other resources, such as carbon, nitrogen, or calcium compounds, but will only be useful once the space economy is sufficiently developed to provide economically interesting uses for them.
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The identification of CCR B
2019-09-07
The identification of CCR6+ GNF 5 within the LZ as direct progenitors of MBCs provides a new window into the evolution of immune responses. In practical terms
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On the other hand p responds to
2019-09-06
On the other hand, p38 responds to environmental stress, including ultraviolet light, heat, osmotic shock, and inflammatory cytokines (Pearson et al., 2001, Kumar et al., 2003), and is activated in astrocytes after ischemia-like injury (Yung and Tolkovsky, 2003, Niu et al., 2009).
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The mechanisms by which Cav enhances
2019-09-05
The mechanisms by which Cav-1 enhances embryonal tumor progression are currently unknown.
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Previous studies have demonstrated the role of the COMT Val
2019-09-04
Previous studies have demonstrated the role of the COMT Val158Met in response to positive and negative emotional stimuli (Bouhuys et al., 1999, Cohn et al., 2009), a fundamental process involved in well-being (Diener et al., 2009a, Diener et al., 1999, Gross and John, 2003).
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MK3102 br Material and methods br Results and discussion br
2019-09-03
Conclusions Prostanoid-E receptor selective antagonists that inhibit EP2 or EP4 receptor activities may be used as a pharmacological strategy to limit cyst formation and ADPKD progression.
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Traditionally serum triglycerides have been measured in the
2019-09-02
Traditionally, serum triglycerides have been measured in the clinic in the fasted state in order to reduce variability and also to facilitate the calculation of LDL-cholesterol via the Friedewald equation, which was derived using fasted samples (Warnick and Nakajima, 2008).
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br Discussion Our data demonstrate that the
2019-08-30
Discussion Our data demonstrate that the bicyclam AMD3100 strongly interacts with CXCR-4, whereas DS and AR177, two other compounds that also interfere with virus entry into the TLR3 (and interfere with virus binding), do not.
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SU11274 Herein we further established a dynamic DNA self
2019-08-29
Herein, we further established a dynamic DNA self-assembly activated hemin-mimetic enzymes system by embedding DNA-hemin into an entropy-driven DNA-assembly for fluorescent biosensing.
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Quercetin competitively inhibited BFC activity in human reco
2019-08-28
Quercetin competitively inhibited BFC activity in human recombinant cDNA-expressed CYP3A4 with Ki=15.4±1.52μM, and myricetin noncompetitively with Ki=74.6±7.99μM (Fig. 4).
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It was demonstrated that ET signaling
2019-08-27
It was demonstrated that ET-1 signaling is the primary axon guidance mechanism that accounts for sympathetic innervation of the sinoatrial node and myocardium in the developing mouse heart [11].
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Employing distinct genetic and pharmacological approaches Di
2019-08-26
Employing distinct genetic and pharmacological approaches, Divakaruni et al. now demonstrate that macrophages still acquire their IL-4-elicited phenotype in the absence of CPT1a (considered the main isoform in leukocytes) or CPT2, and highlight that the increased LC-FAO in M(IL-4) cells is less crucial than previously considered.
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In this study we implicate SCFFBXO E ligase as a
2019-08-24
In this study, we implicate SCFFBXO3 E3 ligase as a critical modulator of inflammation in atherosclerosis and demonstrate the efficacy of a small molecule FBXO3 inhibitor in suppressing inflammatory responses important in atherosclerosis.
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br Materials and methods br Results and
2019-08-23
Conclusions In this study, we have investigated the possibility that hierarchical phosphorylation by CK2 may play a role in cellular signal transduction.
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Downregulation of tumor suppressors is a major factor that
2019-08-22
Downregulation of tumor suppressors is a major factor that leads to tumorigenesis.
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